High Dose Chemo With Autologous BMT for Treatment of Metastatic Breast Cancer
Status
Conditions
Treatments
Details and patient eligibility
About
To evaluate the response rate and the response duration of high dose chemotherapy with autologous bone marrow transplantation as intensification following induction chemotherapy in metastatic breast cancer and to evaluate prospectively the subdivision of patients with metastatic breast cancer according to prognostic groups.
Full description
There are 2 phases to this study: 1) Induction- which consists of the administration of chemotherapeutic drugs- at the end of this phase if the cancer has responded, bone marrow will be collected and frozen untol ready for re-infusion; 2) 2nd phase- involves high-doses of chemotherapy followed by infusion of bone marrow cells
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Histologically confirmed diagnosis of breast cancer
- Age 18-70
- Breast cancer at first clinical evidence of metastatic disease
- Must have objectively measurable or evaluable disease or be in complete remission
Exclusion criteria
- Previous diagnosis of another invasive carcinaom within 10 years (except skin cancer)
- CNS involvement
Trial design
Primary purpose
Allocation
Interventional model
Masking
61 participants in 1 patient group
Trial contacts and locations
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal