High Fat Diet: Oxidative and Cardiovascular Effects (AFN)

Vanderbilt University

Status and phase: Completed; Phase 3

Conditions: Obesity

Treatments: Dietary Supplement: Placebo; Dietary Supplement: MUFA; Dietary Supplement: SFA; Dietary Supplement: PUFA

Study type: Interventional

Funder types: Other

Identifiers

NCT00696228

071325

Details and patient eligibility

About

To test the effects of a modified Atkins high fat diet on endothelial function, insulin resistance and energy balance.

Full description

To test the effects of a modified Atkins high fat diet on endothelial function, insulin resistance and energy balance.

Enrollment: 144 patients

Sex: Female

Ages: 21 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI 30-39.9
• Female
• Age 21-40

Exclusion criteria

• Smoker
• Comorbid Disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

144 participants in 4 patient groups, including a placebo group

AFN A

Placebo Comparator group

Description:

High Fat Diet Placebo

Treatment:

Dietary Supplement: Placebo

AFN B

Experimental group

Description:

MUFA

Treatment:

Dietary Supplement: MUFA

AFN C

Experimental group

Description:

PUFA

Treatment:

Dietary Supplement: PUFA

AFN D

Experimental group

Description:

SFA

Treatment:

Dietary Supplement: SFA