High Flow in Infants With Bronchiolitis

Princess Amalia Children's Clinic

Status: Completed

Conditions: Bronchiolitis

Treatments: Other: Low Flow Nasal Prongs; Other: High Flow Nasal Cannula

Study type: Interventional

Funder types: Other

Identifiers

NCT02913040

High Flow in Bronchiolitis

Details and patient eligibility

About

In this multi-centre randomized controlled trial the investigators compare the effect on dyspnoea severity of oxgen delivery through High Flow Nasal cannula with Low Flow Nasal Prongs in children < 2 years of age hospitalised for bronchiolitis with moderate-severe dyspnoea.

Full description

In this multi-centre randomized controlled trial the investigators compare the effect on dyspnoea severity of oxgen delivery through High Flow Nasal Cannula with Low Flow Nasal Prongs in children < 2 years of age hospitalised for bronchiolitis with moderate-severe dyspnoea. The study will take place on the pediatric (Non intensive care) units of 5 different hospitals in the Netherlands.

Enrollment: 111 patients

Sex: All

Ages: 1 week to 24 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• bronchiolitis PEWS (Pediatric Early Warning Score 0-28) >= 6 oxygen saturation < 92%

Exclusion criteria

• chronic lung disease hemodynamic significant heart disease syndromal disease facial abnormalities

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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111 participants in 2 patient groups

High Flow Nasal Cannula

Experimental group

Description:

Oxygen delivery through Heated Humidified High Flow Nasal Cannula

Treatment:

Other: High Flow Nasal Cannula

Low Flow Nasal Prongs

Active Comparator group

Description:

Oxygen delivery through Low Flow Nasal Prongs

Treatment:

Other: Low Flow Nasal Prongs