High Flow Nasal Cannula as a Treatment for Obstructive Sleep Apnea

Clalit Health Services

Status

Unknown

Conditions

Sleep Apnea, Obstructive

Treatments

Device: High flow nasal cannula

Study type

Interventional

Funder types

Other

Identifiers

NCT03017859

RMC-16-0152

Details and patient eligibility

About

A single center, prospective study to assess the efficacy of high flow nasal cannula (HFNC) in improving obstructive sleep apnea (OSA) parameters in patients with reduced tolerance to continuous positive airway pressure (CPAP) treatment.

Full description

A single center, prospective study. The study would include 30 patients diagnosed within the past 2 years with moderate to severe OSA (AHI>=15) at the Rabin Medical Center (RMC) sleep lab, and who are intolerant to CPAP treatment. Following signing an informed consent form, these patients would undergo polysomnography (PSG) while treated with HFNC. The HFNC PSG outcome measures will be compared to the baseline PSG done within the past 2 years and to an additional PSG while connected to a CPAP device.

Enrollment

30 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 18-80 years
Confirmed diagnosis of obstructive sleep apnea, diagnosed at RMC sleep lab in the past 2 years
Apnea Hypopnea Index (AHI)≥15
Patient has difficulties to adjust or comply with CPAP treatment
Signed Informed Consent Form

Exclusion criteria

Patients who need bilevel positive airway pressure (BIPAP)
Known carbon dioxide (CO2) retainers
Weight change>10% compared to time of OSA diagnosis
Clinically unstable patients
Pregnant women or special populations (e.g. children or patients unable to give informed consent)