High-flow Nasal Cannula for Pediatric Anesthetic Induction

Seoul National University

Status: Completed

Conditions: Oxygen Deficiency

Treatments: Procedure: face mask; Procedure: high flow nasal oxygen

Study type: Interventional

Funder types: Other

Identifiers

NCT05578131

2209-089-1359

Details and patient eligibility

About

Endotracheal intubation in infants often involves more than one attempt, and oxygen desaturation is common. It is unclear whether nasal high-flow therapy, which extends the time to desaturation during elective intubation in infants receiving general anesthesia, can decrease the occurence of desaturation during intubation.

The investigators tested the hypothesis that high-flow nasal oxygen cannulae would be effective in maintaining oxygen saturation during intubation than facemasks for pre-oxygenation. The investigators randomly allocated 132 patients undergoing elective surgery aged <=12 months to pre-oxygenation using either high-flow nasal oxygen or facemask.

Enrollment: 132 patients

Sex: All

Ages: 1 to 12 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infants undergoing general anesthesia with endotracheal intubation.

Exclusion criteria

• infants who diagnosed as cardiorespiratory problem preoperatively.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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132 participants in 2 patient groups

high flow nasal oxygen

Experimental group

Treatment:

Procedure: high flow nasal oxygen

face mask

Active Comparator group

Treatment:

Procedure: face mask