High Flow Nasal Cannula for Safe Apnea

Seoul National University

Status: Completed

Conditions: Apnea; Anesthesia, General

Treatments: Device: Buccal oxygenation; Device: High flow nasal cannula

Study type: Interventional

Funder types: Other

Identifiers

NCT04849520

2102-149-1200

Details and patient eligibility

About

This is a prospective randomized controlled trial comparing high flow nasal cannula and buccal oxygenation as method of oxygenation during apnea in children.

Full description

This is a prospective randomized controlled trial comparing two oxygenation methods for prolongation of apnea time in children aged 0 to 10 years old.

This study measures time for the pulse oximetry drop from 100% to 92% after oxygenation with 100% oxygen, applying high flow nasal cannula or buccal oxygen insufflation via an oral Ring-Adair-Elwyn endotracheal tube connected to oxygen.

Enrollment: 38 patients

Sex: All

Ages: Under 10 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children under 11 years old undergoing general anesthesia with American Society of Anesthesiologists Physical Status 1 or 2.

Exclusion criteria

• Refusal of enrollment from one or more legal guardians of the patient
• Plan of usage of supraglottic airway device as airway maintenance device
• Presence of upper respiratory tract infection of lung disease
• Premature infants younger than postconceptual age of 40 weeks
• Anticipation of difficult bag-mask ventilation due to facial anomaly or micrognathia
• Other conditions that are considered inappropriate for the study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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38 participants in 2 patient groups

High flow

Experimental group

Description:

Application of high flow nasal cannula during apnea

Treatment:

Device: High flow nasal cannula

Buccal

Active Comparator group

Description:

Application of buccal oxygenation during apnea

Treatment:

Device: Buccal oxygenation