High Flow Nasal Cannula in Comparison to Apneic Oxygenation During Foreign Body Removal by Rigid Bronchoscope

Ain Shams University

Status: Unknown

Conditions: Anesthesia

Treatments: Device: Vapotherm; Device: Apneic oxygenation

Study type: Interventional

Funder types: Other

Identifiers

NCT04885673

FMASU R101/2021

Details and patient eligibility

About

To compare the effect of HFNC with standard apneic oxygenation on patient oxygenation and airway protection during foreign body removal by rigid bronchoscope.

Full description

This study is a prospective, randomized controlled trial, at Ain Shams University hospitals, Cardiovascular surgery hospital (Thoracic surgery unit), Cairo, Egypt. We will include 64 patients planned for foreign body removal by rigid bronchoscope. All patients will be ASA І with recent FB aspiration in the last 72hrs either by history or documented by radiopaque shadow in chest X ray or CT scan. After achievement of anesthesia and full muscle relaxation ventilation started by open mask technique. Then the patients will be divided into two groups according to the oxygenation technique:

Group (A) (32 patients) HFNC (Vapotherm) will be used during the bronchoscopy time flow rate 50 L/min with 100% humidified oxygen and the temperature adjusted to be 38℃ .

Group (B) (32 patients) (control group) using the standard apneic oxygenation through the side port of rigid bronchoscope during the procedure

Enrollment: 64 estimated patients

Sex: All

Ages: 10 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• We will include 64 patients planned for foreign body removal by rigid bronchoscope.
• All patients will be ASA І
• Recent FB aspiration in the last 72hrs either by history or documented by radiopaque shadow in chest X ray or CT scan.

Exclusion criteria

• Patients age not more than 40 years old.
• Body weight less than 40 kg.
• Critically ill patients.
• Intubated patients.
• Inhalation of FB more than 72 hrs.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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64 participants in 2 patient groups

Group A (High flow nasal cannula group)

Active Comparator group

Description:

(Vapotherm) will be used during the bronchoscopy time flow rate 50 L/min with 100% humidified oxygen and the temperature adjusted to be 38℃

Treatment:

Device: Vapotherm

Group B (Apeieoc oxygenation group)

Active Comparator group

Description:

The standard apneic oxygenation through the side port of rigid bronchoscope during the procedure

Treatment:

Device: Apneic oxygenation