Efficacy of High-flow Nasal Oxygen in Preventing Hypoxia During Gastrointestinal Endoscopy: a Retrospective Cohort Study

Fengli Liu

Status: Active, not recruiting

Conditions: Hypoxia

Study type: Observational

Funder types: Other

Identifiers

NCT06710613

LY2024-275-B

Details and patient eligibility

About

During painless gastroscopy, the occurrence of hypoxia is a critical concern, especially under intravenous anesthesia using propofol. This study aimed to investigate the incidence of hypoxia during painless gastroscopy and evaluate preventive measures.

Full description

From June 15 th 2023 to August 15th 2023, 900 patients who underwent elective gastroscopy in the Renji Hospital, Shanghai Jiao Tong University School of Medicine were selected. They were divided into the high flow nasal cannula oxygen group and the conventional nasal cannula oxygen group by oxygen inhalation. Patient demographics, Mallampati class, and other relevant factors were compared between the two groups. Primary outcomes included the incidence hypoxia (SpO2 < 90%), while secondary outcomes included subclinical respiratory depression, and adverse events related to nasal oxygen cannula.

Enrollment: 900 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria：

• Patients aged 18 to 70
• Undergoing painless gastroscopy under intravenous anesthesia

Exclusion Criteria：

• Severe respiratory disease
• History of nasal bleeding or mucosal injury
• Emergency cases
• Pregnant or lactating female

Trial design

900 participants in 2 patient groups

control group

Description:

conventional nasal cannula oxygen group

experimental group

Description:

high flow nasal cannula oxygen group