High-flow Nasal Cannula Oxygen Therapy for Ischemic Stroke Patients With Dysphagia and Obstructive Sleep Apnea

Chang Gung Medical Foundation

Status: Completed

Conditions: Cerebral Infarction; Sleep Apnea, Obstructive; Deglutition Disorders

Treatments: Device: high flow nasal cannula ventilation

Study type: Interventional

Funder types: Other

Identifiers

NCT04173767

CMRPG2H0011

Details and patient eligibility

About

High flow nasal cannula (HFNC) ventilation therapy was found to improve the severity of obstructive sleep apnea in non-stroke subjects. The investigators hypothesized that HFNC might be effective in stroke patients with dysphagia who needed nasogastric tube feeding and can not receive continuous positive airway pressure ventilation for obstructive sleep apnea.

Enrollment: 22 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ischemic stroke patients with dysphagia and obstructive sleep apnea who need nasogastric tube feedings

Exclusion criteria

• congestive heart failure, unconsciousness, chronic obstructive pulmonary disease, intracranial hemorrhage or malignancy, and unstable medical and neurological conditions
• central sleep apnea

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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22 participants in 1 patient group

HFNC

Experimental group

Treatment:

Device: high flow nasal cannula ventilation