High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Gastroscopy Sedated by Propofol (HONCHO)

Shanghai Jiao Tong University

Status

Completed

Conditions

Adverse Event

Esophagus Cancer

Gastric Cancer

Hypoxia

Treatments

Device: High-flow nasal cannula oxygenation

Study type

Interventional

Funder types

Other

Identifiers

NCT03332433

RenJiH-20170724

Details and patient eligibility

About

Hypoxia is the most common adverse events during sedated gastroscopy. In present study, high-flow nasal cannula oxygenation will be utilized in order to reduce the hypoxia. At the same time the feasibility and safety will be evaluated.

Enrollment

2,034 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients undergoing gastroscope
age over 18 years old
Signed informed consent form

Exclusion criteria

Coagulation disorders or a tendency of nose bleeding;
An episode/exacerbation of congestive heart failure (CHF) that requires a change in medication, diet or hospitalization from any cause in the last 6 months;
Severe aortic stenosis or mitral stenosis;
Cardiac surgery involving thoracotomy (e.g., coronary artery bypass graft (CABG), valve replacement surgery) in the last 6 months;
Acute myocardial infarction in the last 6 months;
Acute arrhythmia (including any tachycardia - or bradycardia) with hemodynamic instability;
Diagnosed chronic obstructive pulmonary disease or current other acute or chronic lung disease requiring supplemental chronic or intermittent oxygen therapy);
Increased intracranial pressure;
ASA >III;
Mouth, nose, or throat infection;
Fever, defined as core body temperature > 37.5oC ;
Pregnancy, breastfeeding or positive pregnancy test
Emergency procedure