High-flow Nasal Oxygenation During Preoxygenation and Atelectasis

Seoul National University

Status: Enrolling

Conditions: Pulmonary Atelectasis; Anesthesia, General

Treatments: Other: facemask; Other: high-flow nasal oxygen

Study type: Interventional

Funder types: Other

Identifiers

NCT06205212

HFNO_PRE

Details and patient eligibility

About

Atelectasis after induction of general anesthesia is common even in healthy patients and is clinically problematic, especially in obese patients. We aim to investigate whether preoxygenation with high-flow nasal oxygen during anesthesia induction reduces atelectasis in obese patients.

Enrollment: 92 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults patients undergoinig surgery under general anesthesia with a BMI of 30 kg/m2 or greater who have given informed consent

Exclusion criteria

• surgery time less than 2 hours
• Nasotracheal intubation
• Severe cardiac or respiratory disease
• History of difficult airway
• History of a surgery or anatomical anomaly in the head and neck
• History of Inability to breathe through nose
• Gastric reflux disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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92 participants in 2 patient groups

facemask

Active Comparator group

Description:

preoxygenation using a conventional facemask

Treatment:

Other: facemask

high-flow nasal oxygen

Experimental group

Description:

preoxygenation using high-flow nasal cannula oxygen

Treatment:

Other: high-flow nasal oxygen