High-Flow Needleless Valve and DualCap Disinfection Devices Associate With Catheter-related Bloodstream Infection

Peking University

Status and phase: Unknown; Phase 4

Conditions: Catheter-related Bloodstream Infection

Treatments: Device: DualCap Disinfection Devices; Device: High-Flow Needleless Valve

Study type: Interventional

Funder types: Other

Identifiers

NCT02990923

PekingHDNC

Details and patient eligibility

About

The purpose of this study is to investigate whether the usage of High-Flow Needleless Valve and DualCap Disinfection Devices would reduce the incidence of catheter-related bloodstream infection in hemodialysis patients.

Enrollment: 102 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Implanted non-tunneled cuff catheter for any reason and going on blood purified therapy in our centre
• Have signed information consent form

Exclusion criteria

• Have got bacteremia before catheter implantation
• Catheter changing in situ

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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102 participants in 3 patient groups

Control

No Intervention group

Description:

In this group, patients will use traditional standard hemodialysis connector and receive typical disinfection management

Only High-Flow Valve

Experimental group

Description:

In this group, patients will use High-Flow Needleless Valve instead of traditional standard hemodialysia connector, but still receiving typical disinfection management

Treatment:

Device: High-Flow Needleless Valve

Both Divices

Experimental group

Description:

In this group, patients will receive both High-Flow Needleless Valve and DualCap Disinfection Devices in hemodialysis

Treatment:

Device: DualCap Disinfection Devices

Device: High-Flow Needleless Valve