High Flow Oxygen Therapy Effect on Healthy Subjects

Argentinian Intensive Care Society

Status: Completed

Conditions: Diaphragm; Healthy Volunteers; Respiratory Rate

Treatments: Device: High flow nasal canula

Study type: Interventional

Funder types: Other

Identifiers

NCT06086769

CRIHB #1220 PRISA No. 6256

Details and patient eligibility

About

The use of high-flow nasal cannula (HFNC) has increased. Diaphragmatic ultrasonography is a tool that, as a noninvasive complement to esophageal pressure (Pes) measurement, allows the evaluation of diaphragm function and reflects, through the diaphragm thickening fraction (DTf), the magnitude of diaphragmatic fiber recruitment. The objective of this study was to evaluate the impact of HFNC therapy on the DTf in healthy subjects. Second, this study aimed to assess the behavior of the respiratory rate (RR) and the work of breathing in these subjects.

Enrollment: 13 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy subjects over 18 years old

Exclusion criteria

• contraindication for esophageal balloon placement
• diagnosis of lung disease
• smokers

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: Single Blind