High Flow Oxygen With THRIVE Gives Better Oxygenation in Rapid Sequence Induction Patients (THRIVE/RSI 1)

St George's, University of London

Status: Unknown

Conditions: High Flow Oxygen in Rapid Sequence Induction; Airway Morbidity

Treatments: Device: face mask oxygen; Device: High flow oxygen

Study type: Interventional

Funder types: Other

Identifiers

NCT02777840

15/LO/0277

Details and patient eligibility

About

High flow oxygen results in better oxygenation in emergency cases needing rapid sequence induction for anaesthesia. Secondary outcome measure is time for any desaturation.

Full description

The investigators intend to do the study using high flow oxygen for all emergency cases needing rapid sequence induction. As part of the study the Investigators will measure the oxygen levels in the blood gas sample of the patient and the heart rate of anesthetist in charge of the airway management. After the airway is secured the time for desaturation will be noted.

Enrollment: 80 estimated patients

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Emergency patients needing rapid sequence induction for surgery
• ≥ 16 years
• Able to give consent

Exclusion criteria

• Patients age under 16 years
• Inability to give consent
• Severe respiratory disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups

Face mask group

Active Comparator group

Description:

Patients will be given oxygen via face mask as per routine practice, blood gas sample taken after airway is secured, heart rate of anaesthetist monitored and time for desaturation noted.

Treatment:

Device: face mask oxygen

THRIVE group

Active Comparator group

Description:

Patients will be given oxygen via high flow oxygen in Optiflo, blood gas sample taken after airway is secured, heart rate of anaesthetist monitored and time for desaturation noted.

Treatment:

Device: High flow oxygen