High Intensity Exercise and Improving Physical Activity Among People With Neurologic Dysfunction

University of Hartford

Status: Enrolling

Conditions: Charcot Marie Tooth Disease (CMT); Traumatic Brain Injury; Spina Bifida; Stroke; Spinal Cord Injury; Cerebral Palsy (CP)

Treatments: Behavioral: Participate in high intensity exercise of at least 20 minutes in 60 minutes session of RPE greater than 6.

Study type: Interventional

Funder types: Other

Identifiers

NCT06945835

24-10-371

Details and patient eligibility

About

The Hawks in Motion (HIM) High Intensity Exercise program is designed to implement the American Physical Therapy Clinical Practice Guidelines and American College of Sports Medicine recommendations for exercise for people with neurologic disability. Doctor of Physical Therapy (DPT) students administer the HIM High Intensity Exercise Program. A prior study evaluated the feasibility, safety, and efficacy of the HIM High Intensity Exercise Program and found it feasible, safe, and effective for 30 people with neurologic disabilities between the ages of 8-99 years. The investigators would like to evaluate whether participation in the HIM High Intensity Exercise Program affects mobility in everyday life. Physical activity will be measured one week before program implementation and one week after to assess if the participants' mobility in everyday improved.

Full description

The neurological conditions of spinal cord injury (SCI), stroke (CVA), traumatic brain injury (TBI), cerebral palsy (CP), Charcot-Marie-Tooth (CMT), and Parkinson's disease (PD) create a variety of physical impairments that make movement difficult. For example, people with SCI can have complete or partial paralysis of the arms, legs, and or trunk depending on the location and severity of injury. People with CMT have paralysis in specific muscles of the hands, feet, and trunk. Similarly, people with TBI, CVA, and CP can experience increased muscle tone, decreased voluntary movement, and difficulty moving at correct speeds. This makes walking, moving surface to surface, and doing other physical activities difficult, frustrating, and tiring. People tend not to move, and end up with chronic pain, heart disease, diabetes, and poor health. Physical inactivity is one of the most concerning issues among individuals with chronic neurological conditions, often resulting in limited community participation and reduced quality of life. Many individuals with these conditions struggle to achieve sufficient physical activity levels necessary for functional independence and movement in the community, essential for maintaining social connections and overall well-being. Despite the known benefits of moderate-to-vigorous physical activity, challenges persist in improving mobility in community settings. It has been hypothesized that by increasing function and endurance, which the HIM High Intensity Program can do, mobility in everyday life may improve. The purpose of the project is to see if physical activity among individuals with chronic neurological disabilities can be increased by participation in a community-based exercise program. The investigators would like to answer the following research question: Does participation in an 8-week, twice-a-week high-intensity exercise program for people with neurologic disability run by Doctor of Physical Therapy students increase physical activity in the everyday life?

Enrollment: 15 estimated patients

Sex: All

Ages: 8 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• physical disability that limits mobility and activities of daily living, and a neurodevelopmental disability OR neurological disability,
• age 8-99 years of age,
• understands verbal instructions,
• able to obtain medical clearance,
• able to obtain transportation to campus,
• have a parent/guardian/caregiver on site if not own legal authorized representative,
• English speaking.

Exclusion criteria

• no presence of a physical disability that impacts activities of daily living, no neurodevelopmental or neurological disability as an underlying cause,
• no person-centered goals (locomotion, fitness, transfers, and mobility),
• unstable cardiac condition,
• uncontrolled seizures,
• unstable oxygen saturation levels,
• no clearance from primary care physician for exercise,
• unable to read and understand English,
• pursuing active litigation for their physical condition.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

Intervention Arm

Experimental group

Description:

Participants will receive two times a week for 8 weeks one hour of individualized exercise program that is based on clinical practice guidelines for high intensity exercise.

Treatment:

Behavioral: Participate in high intensity exercise of at least 20 minutes in 60 minutes session of RPE greater than 6.