High-intensity Interval Exercise and Chocolate Milk on Blood Glucose and Cognition

Toronto Metropolitan University

Status: Completed

Conditions: Cognitive Function; Glycemic Response

Treatments: Other: Sitting and Chocolate Milk; Other: Sitting and Water; Other: Exercise and Water; Other: Exercise and Chocolate Milk

Study type: Interventional

Funder types: Other

Identifiers

NCT03305107

REB2017- 088

Details and patient eligibility

About

The purpose of this study is to determine the separate and combined effects of high-intensity interval exercise and chocolate milk on glycemic response, cognitive function, subjective appetite, and salivary cortisol among children aged 9-13 year old children.

Full description

Twenty children 9-13 years of age will be recruited for this study. On four separate mornings, after a 10 hour overnight fast, each child will consume a standardized breakfast (including orange juice, a strawberry breakfast bar and a pear fruit cup) at home. Using a 2x2 factorial design, 2 hours after breakfast consumption, each participant will arrive in the lab (T=-20 min) and participate in high-intensity interval exercise or sit quietly for 20 min, followed by a treatment drink of chocolate milk or water (control) consumption in 10 min. During high-intensity interval exercise treatment, children will exercise on a cycle ergometer with a 3-min warm-up, 7 repeated bouts of 60-sec exercise at 90% of peak power output and 60-second recovery, and a 3-min cool down. Blood glucose will be measured via finger-prick at baseline (-20 min), 10, 30, 60, and 90 min. Cognitive functions will be measured using a battery of cognitive tests which assess verbal declarative memory, working memory, and executive functioning, and will be measured at baseline, 10. 30. 60, and 90 min. Subjective appetite and emotions will be measured using a 100-mm visual analogue scale (VAS) at baseline, 10, 30, 60, and 90 min. Salivary cortisol will be assessed from saliva samples collected using the passive drool method, and will be collected at baseline, 10 and 30 min.

Enrollment: 20 patients

Sex: All

Ages: 9 to 13 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• be between 9 and 13 years of age
• be healthy, and have been born at term
• not be taking any medications
• not have allergies to dairy or gluten.

Exclusion criteria

• Food sensitivities, allergies, or dietary restrictions
• Health, learning, emotional, or behavioural problems
• Receiving any medications
• Non-habitual breakfast eater (<5 days/week)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

---

20 participants in 4 patient groups

Exercise and Chocolate Milk

Experimental group

Description:

Children will exercise on a cycle ergometer with a 3-min warm-up, 7 repeated bouts of 60-sec exercise at 90% of peak power output and 60-second recovery, and a 3-min cool down. Children will then drink 240mL of chocolate milk

Treatment:

Other: Exercise and Chocolate Milk

Exercise and Water

Experimental group

Description:

Children will exercise on a cycle ergometer with a 3-min warm-up, 7 repeated bouts of 60-sec exercise at 90% of peak power output and 60-second recovery, and a 3-min cool down. Children will then drink 240mL of water

Treatment:

Other: Exercise and Water

Sitting and Chocolate Milk

Experimental group

Description:

Children will quietly sit for 20 minutes Children will then drink 240mL of chocolate milk

Treatment:

Other: Sitting and Chocolate Milk

Sitting and Water

Experimental group

Description:

Children will quietly sit for 20 minutes Children will then drink 240mL of water

Treatment:

Other: Sitting and Water