High-intensity Interval Exercise in Rheumatoid Arthritis (RA-HIIT)

Vastra Gotaland Region

Status

Active, not recruiting

Conditions

Rheumatoid Arthritis

Treatments

Behavioral: High intensity exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT05768165

Vastra Gotaland record 275642

Details and patient eligibility

About

Cardiovascular performance and overall fitness can be improved by high-intensity aerobic activity, and these benefits may be achievable by persons with rheumatic diseases. The investigators hypothesize that a 12-week high-intensity interval exercise program will provide substantial improvements in cardiovascular function, inflammation and symptoms affecting quality of life.

Enrollment

87 patients

Sex

All

Ages

20 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Rheumatoid arthritis disease according to the American College of Rheumatology (ACR)/ The European Alliance of Associations for Rheumatology (EULAR) 1987/2010 criteria
Disease duration >1 year
Age (range 20-60 years)
Stable medication on anti- rheumatic drugs for >3 months
Low-to-moderate disease activity (<5.1) according to the Disease activity score 28 (DAS28)

Exclusion criteria

Cerebrovascular diseases
Diabetes
Severe hypertension
Chronic obstructive pulmonary disease or other severe pulmonary diseases
Other severe diseases that may be associated with adverse events or restrict participation in high-intensity exercise
Arthroplasty of large joints
Inability to manage Cardiopulmonary Exercise Testing (CPET)
Pregnancy
Already participating in regular aerobic or strength exercise at a high intensity level (>1 hours/ week) during the last 6 months
Inability to speak or read Swedish.