High-Intensity Interval Training and Fat Mass Losses (RIESLING)

Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques

Status: Completed

Conditions: Men; Overweight and Obesity

Treatments: Other: Physical activity

Study type: Interventional

Funder types: Other

Identifiers

NCT05311800

ID-RCB 2019-A02999-48

Details and patient eligibility

About

The aims of this study was to compare two isoenergetic HIIT (High-intensity Interval training) programs (cycling vs. running) on body composition, substrate oxidation at rest and during a moderate exercise, muscle functionality, glycaemic control, lipid profile, inflammation, maximal aerobic capacity (VO2max) and gut microbiota composition in men with overweight or obesity.

The investigators hypothesized that both programs could decrease total, abdominal and visceral fat mass but due to differences in muscle solicitation, metabolism adaptation and blood flow, and that running could favors greater fat mass losses.

Full description

The first aim of this study was to compare two isoenergetic HIIT programs (cycling vs. running) on body composition in men with overweight or obesity.

20 men with overweight or obesity should completed HIIT program three times a week during twelve weeks.

i) High intensity interval training - BIKE (HIIE BIKE) 10 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (37min30s) ii) High intensity interval training - RUN (HIIE RUN) 9 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (35min15s)

Body composition will be measured before and after HIIT program by Dual-energy X-ray absorptiometry (DXA).

Enrollment: 9 patients

Sex: Male

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• men (18 to 65 years old)
• with overweight or obesity (BMI > 25 kg/m2 and ≤ 40 kg/m2)

Exclusion criteria

• medical contraindications to intense physical activity,
• painful joints,
• taking ß-blocker

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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9 participants in 2 patient groups

High intensity interval training - BIKE (HIIE BIKE)

Experimental group

Description:

10 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (37min30s)

Treatment:

Other: Physical activity

High intensity interval training - RUN (HIIE RUN)

Experimental group

Description:

9 cycles of speeding up for 45 s at 80-thPHR followed by pedaling slowly (40% thPHR) for 1m30s (35min15s)

Treatment:

Other: Physical activity