High Intensity Interval Training in Chronic Heart Failure

Inha University Hospital

Status: Enrolling

Conditions: Cardiac Rehabilitation; Chronic Heart Failure

Treatments: Behavioral: Cardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor

Study type: Interventional

Funder types: Other

Identifiers

NCT05659420

InhaUH

Details and patient eligibility

About

The aim of this study is to investigate the effect of high-intensity interval training and moderate intensity continuous training on cardiopulmonary functions in chronic heart failure.

Full description

enroll chronic heart failure patients into 3 randomized controlled group

• high intensity interval training
• moderate intensity continous training
• control

perform cardica rehab for 12 weeks, compare primary and secondary endpoints between baseline and 12 weeks results

Enrollment: 60 estimated patients

Sex: All

Ages: 30 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• medically stable chronic heart failure
• NYHA II-III
• can perform cardiopulmonary exercise test
• after 3months with proper medication
• age 30 to 70
• ejection fraction< 40%

Exclusion criteria

• contraindication to cardiopulmonary exercise test
• musculoskeletal problem who cannot perform cardiopulmonary exercise test
• cognition deficit who cannot understand directions
• severe medial illness

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 3 patient groups, including a placebo group

High intensity interval training

Experimental group

Treatment:

Behavioral: Cardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor

Moderate intensity continous training

Active Comparator group

Treatment:

Behavioral: Cardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor

Control

Placebo Comparator group

Treatment:

Behavioral: Cardiac rehabilitation comprised aerobic exercise on a treadmill accompanied by an electrocardiogram monitoring device and a blood pressure monitor