High Intensity Interval Training in Geriatrics (HIITERGY)

University Hospitals (UH)

Status: Completed

Conditions: Gait, Unsteady; Muscle Weakness

Treatments: Other: high intensity interval training-HIIT; Other: Traditionnal group rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT02318459

13-257 (Other Identifier)

Details and patient eligibility

About

This is a pilot study for evaluating the feasibility of using High Intensity Interval Training in geriatric hospitalized patients compared to the standard current rehabilitation practice.

Full description

High Intensity Interval Training (HIIT) has shown a superior effectiveness and efficiency when compared to Moderate Intensity Continuous Training (MICT) in several types of patients and in healthy subjects. There are no data on HIIT in a general geriatric population. This study is a pilot study evaluating the feasibility of using HIIT in geriatric hospitalized patients compared to the standard current rehabilitation practice without HIIT. It is our desire to perform a larger randomized comparative trial between HIIT and MICT if the pilot study proves its feasibility.

Enrollment: 100 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 65 years and older hospitalized for rehabilitation after an acute medical condition
• Expected duration of the rehabilitation ≥ 2 weeks
• Ability to follow instructions to perform a Timed up and Go Test
• Ability to perform exercises
• Willing to participate in 4 sessions of HIIT per week for 2 weeks

Exclusion criteria

• Any acute condition with tachycardia, hypotension or fever.
• Abnormal cycle ergometer stress test with
• significant ECG modification
• decrease of more than 20 mmHg of the blood pressure with exercise
• angina
• ST depression at a workload <6 METs
• Inability to reach an intensity of 15/20 in the Borg's scale of perceived exertion
• Any unresolved acute medical or surgical condition of the following kind:
• acute heart failure
• acute coronary syndrome < 1 month
• strole < 1 month
• active pericarditis / myocarditis / endocarditis
• thromboembolic disease with < 2 weeks of anticoagulation
• acute infection requiring intravenous treatment
• ongoing intravenous perfusion
• surgery < 2 months
• recent bone fracture
• Previous episode of primary cardiac arrest (ie, cardiac arrest that did not occur in the presence of an acute myocardial infarction or during a cardiac procedure).
• Severe heart failure (NYHA III and IV)
• Severe stenotic or regurgitant valvular disease
• Uncontrolled hypertension at rest (SBP≥160mmHg, DBP≥100mmHg)
• Uncontrolled dysrhythmia
• Non-sustained ventricular tachycardia with exercise
• Implanted defibrillator
• Obstructive cardiomyopathy
• Resting HR > 100/min
• Severe peripheral artery disease
• Severe COPD (VEMS < 50%)
• Exercise-induced asthma
• Oxygen dependency
• Muscular-skeletal anomaly that may limit exercise participation
• Delirium
• Inability to follow instructions
• Inability to consent

Trial design

100 participants in 2 patient groups

high intensity interval training-HIIT

Experimental group

Description:

HIIT 4 times a week, 30 minutes duration

Treatment:

Other: high intensity interval training-HIIT

Traditionnal rehabilitation

Active Comparator group

Description:

Traditionnal group rehabilitation 3 times a week, 1 hour duration.

Treatment:

Other: Traditionnal group rehabilitation