High Intensity Interval Versus Focused Ultrasound on Insulin Resistance in Diabetics With Abdominal Obesity (diabetic)

Badr University

Status: Not yet enrolling

Conditions: Diabetes; Abdominal Obesity; Insulin Resistance

Treatments: Other: Focused ultrasound; Other: High intensity interval exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT06376955

IRB00014233-1

Details and patient eligibility

About

Obesity and diabetes share a common insulin resistance pathway and contribute to chronic hyperglycemia. Both high-intensity interval exercise (HIIE) and focused ultrasound (FUS) have been explored in the context of managing insulin resistance in diabetic individuals with abdominal obesity, though they operate through different mechanisms and have different implications.

Full description

Forty diabetic females aged 25 to 35 years old and body mass index was ≥ 30 kg/m², will participate in this study. They will be assigned into two equal groups, Group A will receive high intensity interval exercise 2 times per week for 4 months in addition to intermitted fasting diet. Group B will receive focused ultrasound 2 times per week for 4 months in addition to intermitted fasting diet. Assessment of abdominal obesity will be applied pre and post treatment through measuring Body mass index (BMI), Waist circumference (WC) in addition to Value of HbA1c and HOMA-IR hormone will be measured to determine effect of treatment on insulin resistance.

Enrollment: 40 estimated patients

Sex: Female

Ages: 25 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

They will be recruited from El_shinnawy physical therapy Centre.

• All are suffering from abdominal obesity
• Their age between 25-35 years old
• Their body mass index more than 30 kg/m2,
• Their waist circumference ranged from 88 cm
• The fat thickness at the treatment area was at least 2.5 cm

Exclusion criteria

• Females having any skin diseases in the abdomen.
• Female suffering from any physical or mental disorders.
• Females suffering from abdominal scars or hernia
• Females didn´t take any medication that might affect their weight all over the study period.
• Females complaining from any cardiovascular disorders.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Group A High intrerval trainig exercise group

Experimental group

Description:

Group A will receive high intensity interval exercise 2 times per week for 4 months in addition to intermitted fasting diet.

Treatment:

Other: High intensity interval exercise

Group B Focused ultrasound group

Experimental group

Description:

Group B will receive focused ultrasound 2 times per week for 4 months in addition to intermitted fasting diet.

Treatment:

Other: Focused ultrasound