High Intensity Resistance and Aerobic Training Among Women With PCOS

Riphah International University

Status: Completed

Conditions: Polycystic Ovary Syndrome

Treatments: Other: High intensity aerobic Exercise Training; Other: High intensity resistance Exercise Training

Study type: Interventional

Funder types: Other

Identifiers

NCT05603169

RiphahIU Mobeena Maqsood

Details and patient eligibility

About

polycystic ovarian syndrome (PCOS) is the most common endocrine female disorder, affecting 4-18% women of reproductive age. The prevalence of PCOS in South Asian women, especially in Pakistani women, is much higher (52%) as compared to white population (20 - 25% in UK). On the basis of cultural, environment, diet and lifestyle practices these women are more prone to development of such disorder. So such public health issue needs to be addressed by strong evidence conducted by a clinical trial. The current study is planned to compare effects of two different exercise protocols of high intensity on anthropometric measures, hormonal profile and quality of life.

Full description

PCOS is a prevalent condition that is affecting adolescent girls now and has serious impacts on menstrual health and quality of life making them prone to early risk development for chronic metabolic diseases. The comparison between high intensity resistance and aerobic training would give results that which one is more effective in gaining benefits and better effects on overall health both physically(menstrual) as well as mentally that would eventually tell us about the quality of life of such patients.

After the initial screening process, the participants fulfilling the Roterdam criteria, willing to participate in the exercise trial will be recruited and then randomized to the allocated groups of either high intensity resistance or high intensity aerobics. At baseline, their anthropometrics measurements, LH/FSH ratios and fasting plasma glucose test will be done. Patient will be called thrice a week for 3 months for training. It is hypothesized that high intensity resistance or high intensity aerobics will improve anthropometric measures along with hormonal profile and quality of life.

Enrollment: 60 patients

Sex: Female

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women diagnosed with PCOS according to Rotterdam criteria
• Age limit: 18-30
• Women who are not part of planned physical activity for the last six months.
• BMI<=30

Exclusion criteria

• Women with PCOS who are already on birth control or hormone therapy.
• Women with PCOS who are already are taking some medication for psychological issues
• Women who are already taking cholesterol control medications.
• Women who are a part of any physical activity already

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

High Intensity Resistance Training

Active Comparator group

Description:

This group will perform high intensity resistance training under supervised physiotherapist in a gym setting. The training load for the first 2 weeks will be 60%-75% of 1RM and increased to 75%-90% of 1RM the following weeks. Load would be increased if the participants will be able to perform 3 sets of 12 repetitions with that load.

Treatment:

Other: High intensity resistance Exercise Training

High Intensity Aerobic Training

Active Comparator group

Description:

This group will perform aerobic training under supervision of a physical therapist in gym setting. To calculate exercise intensity, the HR will be maintained at 75-90% of the maximum (HRmax). The training protocol will begin with a 5-minute warm-up and will end with a 5-minute cool down, during which the HR will be 60-75% of the HRmax. At least 90 min of exercise per week for obese PCOS patients, with treadmill walking that may include whole-body movement involving more than 2/3 of the muscles, the exercise intensity will be high intensity

Treatment:

Other: High intensity aerobic Exercise Training