High Intensity Resistance Training and Possible Sarcopenia

Riphah International University

Status: Completed

Conditions: Sarcopenia

Treatments: Other: High Intensity Resistance Training

Study type: Interventional

Funder types: Other

Identifiers

NCT05985616

REC01549 Shanza Nisar

Details and patient eligibility

About

Studies conducted so far added the dietary supplements along with resistance training as an intervention, we could not determine whether the observed effects of the intervention were due to the training program and/or dietary supplements.

Full description

This study will investigate the effects of high intensity resistance training solely in the possible sarcopenia cases which has not done before, to author's knowledge. Furthermore this study will help clinicians to individualize and optimize the therapy for specific patient subgroups, improve the potential of this therapy to improve human function and well being, facilitate timely interventions in community healthcare and prevention settings, which will contribute to higher awareness of sarcopenia prevention and interventions in diverse health care settings.

Enrollment: 32 patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Both male and female
• Age more than 60 years
• Possible sarcopenia cases as defined by Asian Working Group for Sarcopenia (Handgrip strength: Male less than 26kg and Female less than 18kg, 5 time chair stand test more than/equals to 12 seconds)

Exclusion criteria

• Orthopedic surgery in last one year
• Neurological disorders like stroke etc
• History of recent fractures
• Metabolic disorders like DM etc
• Actively involved in exercise programs
• Cognitive impairment that could confound the assessment
• Wheelchair or bed bound individuals

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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32 participants in 2 patient groups

Group A

Experimental group

Description:

High intensity (80-85% of 1RM) will be administered at alternative days for 16 weeks. The exercise will have three phases; Phase I consists of 2-3 sets of 8-15 repetitions, Phase II will follow the single set approach and Phase III will have the Superset approach. The following activities will be incorporated via resistance training: latissimus front pulleys, rowing, back extension, inverse fly, bench press, shoulder press, lateral raises, butterfly with extended arms, crunches, leg presses, leg extension and curls, leg adduction, abduction.

Treatment:

Other: High Intensity Resistance Training

Group B

No Intervention group

Description:

No intervention will be provided in this group. The participants in this group will follow their usual daily activities.