High Plasma Level of Long Pentraxin 3 is Associated With Insulin Resistance in Women With Polycystic Ovary Syndrome (PCOS)

Gulhane School of Medicine

Status: Completed

Conditions: PCOS

Study type: Observational

Funder types: Other

Identifiers

NCT01463969

23.10.2011

24.05.2011 (Registry Identifier)

Details and patient eligibility

About

In the present study, serum pentraxin 3 level and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS. It was found that PTX3 level is increased in patients with PCOS and it is positively correlated with HOMA-IR.

Enrollment: 80 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Absence of significant abnormalities on physical examination except hirsutism
• No lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy
• Normal thyroid function and prolactin level
• Absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease

Exclusion criteria

• Pregnant
• Possible ovarian tumors,
• Congenital adrenal hyperplasia or
• BMI greater than 35 kg/m2

Trial design

80 participants in 2 patient groups

PCOS patients

Control group