High Resolution Anuscopy Study

Universitair Ziekenhuis Brussel

Status: Enrolling

Conditions: Human Papilloma Virus; Anal Squamous Cell Carcinoma

Treatments: Other: HRA

Study type: Observational

Funder types: Other

Identifiers

NCT06697964

HRA Study

Details and patient eligibility

About

The majority of anal squamous cell carcinomas (SCC) stem from infection with high-risk human papillomavirus (HPV). Anal SCC is rare among the general population but affects several populations disproportionately.

High-risk groups are screened through anal swabs for anal cytology and detection of high risk human papillomavirus (HR HPV). HRA referral is recommended for individuals with abnormal cytology.

HRA represents the only method to identify precancerous lesions of the anal canal, with only few specialists knowledgeable about it.

At UZ Brussel, the investigators collected a wealth of data about HPV infection and its association with anal pathology. By establishing a comprehensive study, the investigators can delve into this data with specific research questions, conducting valuable research to provide answers to pressing clinical questions and contribute to advancements in medical understanding and treatment.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients who have undergone HRA and all future patients referred for HRA in UZ Brussel
• 18 years or older
• Understands and able to speak and write in French, Dutch or English

Exclusion criteria

• None