High Resolution HBA-MRI Using Deep Learning Reconstruction

Seoul National University

Status: Active, not recruiting

Conditions: Deep Learning; Magnetic Resonance Imaging; Liver Diseases

Treatments: Diagnostic Test: Liver MRI

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT05182099

2021-3044

Details and patient eligibility

About

This study aims to compare image qualities between conventionally reconstructed MRI sequences and deep-learning reconstructed MRI sequences from the same data in patients who undergo Gd-EOB-DTPA enhanced liver MRI. The AIRTM deep learning sequence is applicable for various MRI sequences including T2-weighted image (T2WI), T1-weighted image and diffusion-weighted image (DWI). We plan to perform intra-individual comparisons of the image qualities between two reconstructed image datasets.

Enrollment: 52 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• older than 20 years old
• scheduled for Gd-EOB-DTPA enhanced liver MRI at a 3T scanner (Premier, GE Healthcare) in our institution
• signed informed consent

Exclusion criteria

• younger than 20 years old
• any absolute/relative contrast indication of Gd-EOB-DTPA enhanced MRI
• history of transient dyspnea after Gd-EOB-DTPA administration

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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52 participants in 2 patient groups

Conventional image reconstruction

Other group

Description:

Gd-EOB-DTPA enhanced liver MRI images are reconstructed using a conventional image reconstruction algorithm. It is automatically generated from a MRI console after the examination.

Treatment:

Diagnostic Test: Liver MRI

Deep learning image reconstruction

Active Comparator group

Description:

Gd-EOB-DTPA enhanced liver MRI images are reconstructed using a deep learning based image reconstruction algorithm (AIRTM). It is additionally generated aside from the conventional images. For obtaining the images, we will use the same MRI raw data which is used for conventional image reconstruction.

Treatment:

Diagnostic Test: Liver MRI