High Risk of Death or Disability in Brain Hemorrhage: Role of Spot Sign and Secondary Markers

Centre Hospitalier de Gonesse

Status: Not yet enrolling

Conditions: Brain Injuries; Cerebral Hemorrhage; Stroke; Intracerebral Hemorrhage

Study type: Observational

Funder types: Other

Identifiers

NCT07172542

0125_REANIMATION_SPOT-TARGET

Details and patient eligibility

About

This study looks at patients with brain hemorrhage to see if a special sign on brain scans, called the "Spot Sign," combined with other scan features, can predict a higher risk of death or disability. By comparing patient outcomes with existing prediction scores, the study aims to understand whether these scan markers provide extra value in identifying patients at higher risk.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Spontaneous intracerebral hemorrhage confirmed by contrast-enhanced CT scan.
• Follow-up CT scan performed within 24 to 48 hours.

Non-inclusion Criteria :

• Absence of initial contrast-enhanced CT or follow-up CT.
• Hematoma due to trauma, epidural hematoma (EDH), subdural hematoma (SDH), or subarachnoid hemorrhage (SAH).

Exclusion criteria

• Patient deceased before the initial contrast-enhanced CT.
• Major missing clinical data.

Trial design

50 participants in 4 patient groups

Intracerebral Hemorrhage Without Spot Sign or Secondary Morphological Marker

Spot Sign Only

Spot Sign With a Secondary Morphological Marker

Single Secondary Morphological Marker Without Spot Sign