High Sensitive C-reactive Protein to Albumin Ratio in Acute Coronary Syndrome

Sohag University

Status: Enrolling

Conditions: Acute Coronary Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT06673381

AEMorsy

Details and patient eligibility

About

assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in prediction of in-hospital short-term major adverse cardiac events (MACEs) in acute coronary syndrome (ACS) patients

Full description

Observational study conducted at coronary care unit(CCU) in sohag university hospital It included patients with ACS diagnosed according to AHA/ACCF guidelines (according to symptoms, ECG findings and serum troponin levels), who had admitted to the CCU.

Venous blood samples were instantly collected on admission to the hospital. hs-CRP , serum albumin level were measured.

hs-CAR is calculated and the patients divided into two groups: Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR) In-hospital MACE was regarded as the end point of our study. It was defined as acute heart failure, cardiogenic shock, reinfarction, all-cause death, serious arrhythmia and cardiac death

Enrollment: 240 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients aged 18 Year or older presented by ACS not candidet for primary percutaneus coronary intervention ( PCI ) .

Exclusion criteria

• • Patients aged < 18 years old

  • Patients who have eGFR <60 ml/kg /m2
  • Patients who have malignancies
  • Patients who have chronic heart failure (NYHA class >II)
  • Pateints who have chronic liver disease
  • Patients who have nephrotic syndrome
  • Patients who have acute cerebrovascular stroke
  • Pregnant women
  • Patients who have recent infection

Trial design

240 participants in 1 patient group

high sensitive c-reactive protein to albumin ratio (hs-CAR)

Description:

Group A ( patients with high hs-CAR) and group B ( patients with low hs-CAR)