High Sensitive CRP in Prediabetics and Diabetes

Fayoum University

Status: Completed

Conditions: Assess Level of High Sensitive CRP in Diabetics and Prediabetics

Study type: Observational

Funder types: Other

Identifiers

NCT03673904

D84

Details and patient eligibility

About

The aim of this study was to study the level of high-sensitivity CRP in sera of pre-diabetic and newly diagnosed patients with type 2 diabetes mellitus and its correlation with HOMA IR and HbA1c

Full description

This study will include (180) subjects, 60 pre-diabetic patients, 60 patients with newly diagnosed type 2 diabetes ( within one month of diagnosis) and 60 normal healthy non diabetic individuals as a control group. The study individuals will be recruited from the Diabetes and Internal Medicine Clinics of Fayoum University Hospital

Enrollment: 180 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pre-diabetic patients:

  • A fasting blood glucose level (100 to 125 mg/dL). or
  • A 2-hour blood glucose level (140 to 199 mg/dL) .or
  • Hb A1C 5.7% to 6.4%.

• Newly diagnosed type 2 diabetes: (maximum within one month from diagnosis)

  • A fasting blood glucose level >126 mg/dl
  • A 2-hour blood glucose level > 200 mg/dl
  • Hb A1C > 6.5%

Exclusion criteria

• Pregnant or lactating females.
• Patients who have recent infection.
• Patients with acute inflammatory diseases as autoimmune diseases.
• Patients with malignancy or on chemotherapy.
• Patients with acute or chronic liver or renal diseases

Trial design

180 participants in 2 patient groups

Prediabetics

Description:

Ages ranging from 18 to 60 years old,males and females were included . A fasting blood glucose level (100 to 125 mg/dL). or A 2-hour blood glucose level (140 to 199 mg/dL) .or Hb A1C 5.7% to 6.4%.

Newly diagnosed type 2 diabetes

Description:

Ages ranging from 18 to 60 years old,males and females were included Newly diagnosed type 2 diabetes: (maximum within one month from diagnosis) A fasting blood glucose level \>126 mg/dl A 2-hour blood glucose level \> 200 mg/d Hb A1C \> 6.5%