High Tibial Osteotomy for Osteoarthritis of the Knee (HTO)

Erasmus University

Status: Completed

Conditions: Osteoarthritis

Treatments: Procedure: Opening-wedge HTO; Procedure: Closing-wedge HTO

Study type: Interventional

Funder types: Other

Identifiers

NCT01977261

2001-HTO

Details and patient eligibility

About

A prospective, randomised, controlled trial compared two different techniques of high tibial osteotomy with a lateral closing wedge or a medial opening wedge, stabilised by a Puddu plate. The clinical outcome and radiological results were examined at one year.

Full description

A prospective, randomised, controlled trial compared two different techniques of high tibial osteotomy with a lateral closing wedge or a medial opening wedge, stabilised by a Puddu plate. The clinical outcome and radiological results were examined at one year.

The primary outcome measure was the achievement of an overcorrection of valgus of 4°. Secondary outcome measures were the severity of pain (visual analogue scale), knee function (Hospital for Special Surgery score), and walking distance.

Enrollment: 92 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Radiological OA, medial joint pain and varus malalignment

Exclusion criteria

• Symptomatic OA of the lateral compartment, rheumatoid arthritis, ROM <100, collateral ligament laxity, history of fracture of previous open operation of the lower limb and a flexion contracture > 10 degrees.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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92 participants in 2 patient groups

Opening-wedge HTO

Experimental group

Description:

Opening-wedge high tibial osteotomy fixated with a Puddu-plate

Treatment:

Procedure: Opening-wedge HTO

Closing-wedge HTO

Active Comparator group

Description:

Closing-wedge high tibial osteotomy fixated with 2 staples

Treatment:

Procedure: Closing-wedge HTO