High Tibial Osteotomy With/Without Arthroscopy.

Centre of Postgraduate Medical Education

Status: Unknown

Conditions: Meniscus; Degeneration; Osteoarthritis, Knee

Treatments: Procedure: Micro fractures; Procedure: Arthroscopy treatment; Procedure: HTO

Study type: Interventional

Funder types: Other

Identifiers

NCT05128851

HTO_artro

Details and patient eligibility

About

This study will compare Hight Tibial Osteotomy with or without arthroscopically repair intra-articular knee lesions in patients with early stages of Osteoarthritis.The purpose of this study is evaluate if addition of arthroscopy to HTO provides better clinical, radiological and laboratory outcomes.

Full description

Intraarticular knee lesions are often in patients with early stages of osteoarthritis. The most frequent findings are degenerative meniscus/meniscal tears and cartilage degeneration. Degenerative meniscal lesions or meniscal tears are often incidental findings without any complains from patients. In the current literature there is no evidence for good clinical outcomes after arthroscopically treatment degenerative meniscus. Cartilage injuries are common in osteoarthritic knee and depending on grading of chondromalacia are usually treated by microfractures. By this time the choice of performed surgery depends on surgeons personal assessment. The investigators believe that concomitant intraarticular procedures added to HTO will provide better clinical outcomes.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Knee medial compartment or patellofemoral osteoarthritis in medical interview and physical examination
• Intraarticular lesions in MRI
• Confirmation of cartilage degeneration/damage and knee malalignment in radiological tests

Exclusion criteria

• no informed consent to participate in the study
• age under 18 years or above 65
• multilligament injury or single plane knee instability
• another musculoskeletal disorders in lower limb
• lower limb deformity requiring axis correction below 4o or above 12.5o • joints inflammatory diseases
• ASA score > II

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 3 patient groups

High Tibial Osteotomy and arthroscopy

Active Comparator group

Description:

High Tibial Osteotomy with arthroscopically treatment of intraarticular lesions.

Treatment:

Procedure: Arthroscopy treatment

Procedure: HTO

High Tibial Osteotomy

Sham Comparator group

Description:

Descending High Tibial Osteotomy with arthroscopy without treatment of intraarticular lesions.

Treatment:

Procedure: HTO

High Tibial Osteotomy, arthroscopy and microfractures

Active Comparator group

Description:

High Tibial Osteotomy with arthroscopically treatment of intraarticular lesions and microfracture.

Treatment:

Procedure: Arthroscopy treatment

Procedure: Micro fractures

Procedure: HTO