Highly Cross-linked Polyethylene in Total Knee Arthroplasty

Ewha Womans University

Status and phase: Completed; Phase 4

Conditions: Knee Arthroplasty, Total

Treatments: Procedure: Total knee arthroplasty with HXLPE liner; Procedure: Total knee arthroplasty with conventional polyethylene liner

Study type: Interventional

Funder types: Other

Identifiers

NCT03622398

XPEPETKA

Details and patient eligibility

About

The aim of this study was to determine clinical and radiographic results after posterior cruciate-substituting total knee arthroplasties with highly cross-linked polyethylene in one knee and compression mold conventional polyethylene in the contralateral knee in the same patients.

Enrollment: 125 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Younger than 65 years old
• with end stage knee arthritis bad enough for knee replacement

Exclusion criteria

• inflammatory arthritis
• combined foot and ankle disorders.
• dementia
• patient older than 65 years old.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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125 participants in 2 patient groups

HXLPE

Experimental group

Description:

This side of knee implanted with HXLPE(highly crosslinked polyethylene) liner while undergoing total knee arthroplasty. This group will receive the intervention, "Total knee arthroplasty with HXLPE liner".

Treatment:

Procedure: Total knee arthroplasty with HXLPE liner

Conventional

Active Comparator group

Description:

This side of knee implanted with conventional polyethylene while undergoing standard total knee arthroplasty. This group will receive the intervention, "Total knee arthroplasty with conventional polyethylene liner".

Treatment:

Procedure: Total knee arthroplasty with conventional polyethylene liner