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HIIT Versus MICT in COPD: Effects on Oxygenation, Pulmonary Function, and Strength

A

Aynur Demirel

Status

Not yet enrolling

Conditions

Chronic Obstructive Pulmonary Disease (COPD)

Treatments

Other: HIIT GROUP
Other: MICT

Study type

Interventional

Funder types

Other

Identifiers

NCT07109687
BSV-000021

Details and patient eligibility

About

Chronic Obstructive Pulmonary Disease (COPD) is a progressive condition marked by airflow limitation and chronic inflammation, leading to reduced exercise capacity, peripheral muscle dysfunction, and dyspnea. High-Intensity Interval Training (HIIT) may offer a promising alternative for patients with low exercise tolerance; however, evidence on its effectiveness remains limited.

This study aims to compare the effects of HIIT and Moderate-Intensity Continuous Training (MICT) on muscle oxygenation, pulmonary function, exercise capacity, and peripheral muscle strength in individuals with COPD. Participants will undergo an 8-week exercise program, twice weekly. HIIT will consist of 1-minute intervals at 90% and 30-40% of peak workload, while MICT will involve continuous cycling at 65% of peak workload. Outcomes will be assessed at baseline, week 4, and week 8. Data will be analyzed using SPSS. This study seeks to determine the more effective training modality to optimize COPD rehabilitation.

Enrollment

40 estimated patients

Sex

All

Ages

40 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Diagnosed with Chronic Obstructive Pulmonary Disease (COPD),
  • GOLD stage 2, 3, or 4,
  • Willing to participate in the study,
  • Aged between 40 and 80 years,
  • Clinically stable (no significant deterioration in the current medical condition, no recent initiation of a new treatment, and no complications requiring hospitalization).

Exclusion criteria

  • Presence of visual, auditory, vestibular, cognitive, or neurological impairments that may affect balance,
  • Any orthopedic, neurological, or cardiac conditions that may interfere with study participation or exercise,
  • Presence of serious chronic diseases such as congestive heart failure, coronary artery disease, or chronic renal failure,
  • Conditions that may cause physical limitations (e.g., limb amputation, significant musculoskeletal disorders, or postural abnormalities such as kyphosis or lordosis).

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

40 participants in 2 patient groups

Control Group
Active Comparator group
Description:
standard aerobic exercise will apply in moderate intensity continuous training.
Treatment:
Other: MICT
interval exercise group
Experimental group
Treatment:
Other: HIIT GROUP

Trial contacts and locations

0

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Central trial contact

Aynur Demirel, PT, PhD, Assoc. Prof.; Irem Suzen, PT MsC

Data sourced from clinicaltrials.gov

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