HIPEC Surgery and Hemodynamics

Miray Gözde Özdemir

Status: Not yet enrolling

Conditions: Hyperthermic Intraperitoneal Chemotherapy (HIPEC); Cytoreductive Surgery; Hemodynamics

Study type: Observational

Funder types: Other

Identifiers

NCT06922227

530

Details and patient eligibility

About

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) involves the intraoperative administration of heated chemotherapeutic agents into the abdominal cavity following cytoreductive surgery (CRS). The increasing use of CRS combined with HIPEC has introduced certain procedural and physiological considerations that distinguish it from other surgical interventions, posing unique challenges for researchers and clinicians alike.

Despite advancements in surgical and anesthetic techniques, this combined approach is frequently associated with significant hemodynamic instability, coagulation abnormalities, respiratory complications, and nutritional imbalances.

The study aims to contribute to the existing body of knowledge by examining the physiological alterations induced by HIPEC, thereby offering practical insights and guidance for investigators involved in the management and study of this complex therapeutic modality.

Enrollment: 15 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ≥18 years old Patients planned to undergo cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
• ASA II-III-IV physical class

Exclusion criteria

• <18 years
• Emergency cases

Trial design

15 participants in 1 patient group

Group 1

Description:

Patients who will undergo HIPEC with cytoreductive surgery