Histologic Comparison of Ablative Techniques for Endometriosis

TriHealth

Status: Enrolling

Conditions: Endometriosis Pelvic; Endometriosis-related Pain; Endometriosis; Endometriosis; Peritoneum

Treatments: Device: Argon Beam Coagulator; Device: CO2 Laser; Device: Diathermy

Study type: Interventional

Funder types: Other

Identifiers

NCT06414083

24-007

Details and patient eligibility

About

To our knowledge, no other human studies directly compare the effectiveness of the various ablative technologies. We set out to design a study to directly compare ablative energy sources and evaluate their ability to destroy native endometriosis tissue in humans.

Enrollment: 141 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult women 18 years of age or older
• Already planning to undergo scheduled robotic assisted or laparoscopic excision of lesions for pelvic pain symptoms (pelvic pain, dysmenorrhea, dyspareunia, dysuria, dyschezia, ovarian pain) or endometriosis of any kind (endometriosis of any location, or endometrioma)

Exclusion criteria

• Known pregnancy at enrollment or at the time of the excision surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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141 participants in 3 patient groups

Diathermy

Active Comparator group

Treatment:

Device: Diathermy

CO2 Laser

Active Comparator group

Treatment:

Device: CO2 Laser

Argon Beam Coagulator

Active Comparator group

Treatment:

Device: Argon Beam Coagulator