Histological and Imaging Assessment of the Structural Characteristics of the Femoro-popliteal Arterial Segment

University Hospital, Strasbourg, France

Status: Unknown

Conditions: Chronic Limb Ischemia

Treatments: Procedure: Explantation of the femoro-popliteal arterial segment from the amputed limb

Study type: Observational

Funder types: Other

Identifiers

NCT03847597

7168

Details and patient eligibility

About

The femoro-popliteal arterial segment is one of the most frequent locations for atherosclerosis. Its management is mainly endovascular (standard and coated-balloon angioplasty, stenting).

However, the structural features of the atherosclerotic disease in regards to patient's risk factors and past medical and surgical histories are not well studied. Furthermore, the histological analysis of the femoro-popliteal arterial segment is rare in the literature, and made difficult mostly because of the length of this segment.

There is a clinical need for better understanding of atherosclerotic lesions in this location, with as further goal, a better management of this disease.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years old
• Men and women
• Patient with chronic limb ischemia that is scheduled for transfemoral amputation in the University Hospital of Strasbourg
• Patient giving his -non-opposition to the explantation and use of the femoro-popliteal arterial segment

Exclusion criteria

• Refusal to give his consent
• Impossibility to give clear information to the patient
• Pregnant and breastfeeding women
• Patient under administrative protection