Histomorphometric and Tomographic Assessment on the Influence of the Placement of a Collagen Membrane Subjacent the Sinus Mucosa After Maxillary Sinus Floor Augmentation

ARDEC Academy

Status

Completed

Conditions

Alveolar Bone Loss

Treatments

Procedure: Maxillary sinus augmentation

Study type

Interventional

Funder types

Other

NETWORK

Identifiers

NCT03902457

CBCT sinus membrane

Details and patient eligibility

About

the purpose of the study is to look for differences in dimensional variations of augmented maxillary sinuses with or without the placement of a collagen membrane subjacent the sinus mucosa.

Full description

Material and Methods: After the elevation of the maxillary sinus mucosa, a collagen membrane with standard dimensions will be placed at the test sites subjacent the sinus mucosa and the elevated space will be filled with a xenograft, both test and control groups. A collagen membrane will be placed to cover the antrostomy at both groups and sutures will be provided to close the wound. After six months of healing, mini-implants will be installed. After 9 months, biopsies containing the mini-implants will be harvested for histomorphometric analyses. CBCTs will be taken for all patients before surgery (T0), after 1 week from sinus floor augmentation (T1) and after 9 months of healing (T2). Osseointegration of the mini-implants and dimensional changes over time of soft and hard tissues will be evaluated on the CBCTs.

Enrollment

20 patients

Sex

All

Ages

21+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

presence of an edentulous atrophic zone in the posterior segment of the maxilla
height of the sinus floor ≤4 mm
desiring a prosthetic restoration of the zone using a fix prosthesis supported by implants;
≥ 21 years of age
good general health
no contraindication for oral surgical procedures
not being pregnant

Exclusion criteria