Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Injury or Chronic Kidney Disease in Routine Practices (NEPHROCT)

Centre Hospitalier William Morey - Chalon sur Saône

Status

Enrolling

Conditions

Chronic Kidney Diseases

Acute Kidney Injury

Tomography, Optical Coherence

Treatments

Other: Dynamic full-field optical coherence tomography analysis of kidney biopsy

Study type

Observational

Funder types

Other

Identifiers

NCT05728216

NEPHROCT

Details and patient eligibility

About

Kidney biopsy play a key role for the investigation of either acute kidney injury or chronic kidney disease. Despite possible complications due to the invasive nature of the biopsy, such procedure is still essential in a number of clinical situations to improve the diagnosis specificity of kidney disease, better inform about its prognosis and guide the management of a future treatment. Pursuing the idea to improve both performance and rapidity associated with the histopathological analysis of kidney biopsy, with a possible recourse to artificial intelligence-based renal pathology, the present study intends to assess the impact of direct histopathological examination of kidney biopsy with dynamic full-field optical coherence tomography in routine practices for the diagnosis of either acute kidney injury or chronic kidney disease.

Enrollment

50 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients > 18 years of age with suspected acute kidney injury requiring biopsy in the nephrology department
patients > 18 years of age with suspected chronic kidney disease requiring biopsy in the nephrology department

Exclusion criteria