Histopathological Changes in Mycosis Fungoides

Bezmialem Vakif University

Status: Enrolling

Conditions: Mycosis Fungoides

Treatments: Diagnostic Test: biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT05904522

mf-E.84376

Details and patient eligibility

About

Patients with mycosis fungoides stage 1A disease have patch and plaque lesions less than %10 of body skin area. Aim of the study is to compare lesional and non-lesional skin of mycosis fungoides patients, and to decide if the systemic treatment is better or local treatment is better for them. Two biopsies for each patient were taken from lesional and non-lesional skin area.

Full description

Patients with mycosis fungoides stage 1A disease have patch and plaque lesions less than %10 of body skin area. Aim of the study is to compare lesional and non-lesional skin of mycosis fungoides patients, and to decide if the systemic treatment is better or local treatment is better for them. Two biopsies for each patient were taken from lesional and non-lesional skin area.

Biopsies will be taken from lesional and non-lesional skin of the patients in the dermatology clinic and sent to laboratory for histopathologic examination.

Enrollment: 10 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histopathologically confirmed mycosis fungoides stage 1A patients

Exclusion criteria

• Mycosis fungoides patients with other stages

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

lesional skin

Experimental group

Description:

lesional skin of mycosis fungoides stage 1A patients

Treatment:

Diagnostic Test: biopsy

non-lesional skin

Experimental group

Description:

non-lesional skin of mycosis fungoides stage 1A patients

Treatment:

Diagnostic Test: biopsy