Histopathological Diagnosis of Adenomyosis

Woman's Health University Hospital, Egypt

Status: Completed

Conditions: Adenomyosis

Treatments: Procedure: hysteroscopic endo-myometrial biopsy; Device: ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT02340533

AD0152015

Details and patient eligibility

About

The purpose of this study is to develop and evaluate a hysteroscopic endo-myometrial biopsy for diagnosing adenomyosis.

Enrollment: 200 estimated patients

Sex: Female

Ages: 38 to 52 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• females complaining of pelvic congestion: dysmenorrhea, dyspareunia, chronic pelvic pain, menorrhagia, metrorrhagia

Exclusion criteria

• refusal of the patient to get enrolled in the study

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

---

200 participants in 1 patient group

adenomyosis

Experimental group

Description:

females attending the gynecology outpatient clinic complaining of chronic pelvic congestion will get enrolled in the study. Two dimensional ultrasonography will be performed to asses the presence or absence of adenomyosis or any associated lesions. All the patients were then be subjected to office hysteroscopy and endo-myometrial biopsies will be taken. Histopathological examination of the samples will then be done. From these recruited patients, some will be indicated to perform hysterectomy. The final diagnosis will then be based on the histopathological examination of the specimen retrieved from hysterectomy. The accuracy of the ultrasound and the hysteroscopic endo-myometrial biopsy will then be compared and assessed.

Treatment:

Device: ultrasound

Procedure: hysteroscopic endo-myometrial biopsy