HIT in Insulin-resistant and Insulin-sensitive Obese Adolescents

Faculdade de Ciências Médicas da Santa Casa de São Paulo

Status: Completed

Conditions: Adolescents; Obesity; Insulin-resistant

Treatments: Other: Group Insulin-Resistant; Other: Group Insulin-Sensitive

Study type: Interventional

Funder types: Other

Identifiers

NCT03042234

japarecido

34634414.5.0000.5479 (Registry Identifier)

1.227.250 (Other Identifier)

Details and patient eligibility

About

Evaluate the effects of HIT on the cardiorespiratory performance and substrate oxidation of insulin-resistant and insulin-sensitive obese adolescents.

Full description

Objective: To evaluate the effect of high-intensity interval training (HIT) on the cardiorespiratory performance and substrate oxidation pattern in insulin-resistant and insulin-sensitive obese adolescents.

Enrollment: 25 patients

Sex: All

Ages: 12 to 16 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Criteria

Inclusion Criteria:

• aged 12-16 years
• with a body mass index z-score (zBMI) ≥ + 2SD
• puberty stage > 3
• the boys and girls had to present a minimum physical fitness, according to the International Physical Activity Questionnaire (IPAQ), according to the activity performed during the last week and confirmed this using the peak cardiopulmonary test (VO2).

Exclusion Criteria:

• individuals undergoing drug treatment for weight control;
• indiviudals who had cardiac, orthopedic, respiratory or renal problems, diabetes, uncontrolled hypertension, genetic syndrome or hormonal abnormalities.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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25 participants in 2 patient groups

Group Insulin-resistant

Experimental group

Description:

Insulin-resistant obese adolescents

Treatment:

Other: Group Insulin-Sensitive

Other: Group Insulin-Resistant

Group Insulin-sensitive

Experimental group

Description:

Insulin-sensitive obese adolescents

Treatment:

Other: Group Insulin-Sensitive

Other: Group Insulin-Resistant