HLA and it Relation With the Development of Proliferative Diabetic Retinopathy in Mexican Population

Asociación para Evitar la Ceguera en México

Status and phase: Withdrawn; Phase 3

Conditions: Diabetes Mellitus Type 2; Proliferative Diabetic Retinopathy

Treatments: Procedure: blood sample

Study type: Interventional

Funder types: Other

Identifiers

NCT00600236

APEC-0018

Details and patient eligibility

About

One of the first causes of irreversible blindness in mexican population is diabetic retinopathy which is clearly diferent between patients the time of evolution and development of retinopathy and complications. The aim of this study is to explore the inmunogenetic profile and the influence of HLA in this variations of the sickness to predict the severity of diabetic complications.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetes mellitus type 2 with 10 years of diagnosis and no diabetic retinopathy
• Diabetes mellitus type 2 with 10 years of diagnosis and proliferative retinopathy

Exclusion criteria

• Systemic hipertension
• Cardic disease
• Lupus
• Any kind of artritis
• Allergies
• Optic Neuritis
• VKH
• Cancer
• Inmunological diseases

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind