HLA Antibodies in Systemic Lupus Erythematosus (LEDHLA)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: HLA Antibodies; Systemic Lupus Erythematosus

Study type: Observational

Funder types: Other

Identifiers

NCT06921239

PI2025_843_0043

Details and patient eligibility

About

Patients suffering from autoimmune diseases show false-positive results when anti-HLA antibodies are identified. This false positivity makes it difficult to obtain an organ transplant based on immunological compatibility (absence of anti-HLA antibodies directed against graft antigens). The objectives of this project are to study the prevalence of these false positivities in a population of lupus patients, and to evaluate biological tests that can negate these false positivities.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients Adults
• Followed in the internal medicine department of Amiens University Hospital - With systemic lupus erythematosus
• Without HLA immunization risk factors (no history of pregnancy, transfusions or transplants)
• With sera stored in the biobank

Exclusion criteria

• minor Patients
• Opposing the re-use of their personal data for research purposes