HLA Sensitization in Severely Burned Patients

University of Zurich (UZH)

Status: Unknown

Conditions: Severely Burned Patients

Study type: Observational

Funder types: Other

Identifiers

NCT02537821

PKSF-01-2014

Details and patient eligibility

About

Primary goal of this study is the analysis of HLA (Human leucocyte antigen) formation in severly burned patients. Potential HLA triggers in the treatment of severely burned patients are blood products, assist devices or temporary allogeneic skin. Besides that, inflammatory markers, such as WBC (white blood cell count), CRP (C-reactive protein), PCT (Procalcitonin) and two novel biomarkers (PSP (pancreatic stone protein), ST2) are to be investigated in severely burned patients.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• severely burned patients in need for hospitalization

Exclusion criteria

• hematologic diseases
• Cancer