HoLEP vs BPRP in the Management of a Large Volume (> 80 gm) Symptomatic BPH

Cairo University (CU)

Status: Completed

Conditions: BPH With Urinary Obstruction; Male

Treatments: Procedure: holmium laser enucleation of the prostate; Procedure: Bipolar resection of the prostate

Study type: Interventional

Funder types: Other

Identifiers

NCT04935151

REC-TBRI-PT563

Details and patient eligibility

About

To compare bipolar resection versus holmium laser enucleation for management of symptomatic large BPH (> 80 gm)

Full description

To compare safety and efficacy of bipolar resection (BPRP) versus holmium laser enucleation (HoLEP) for management of symptomatic large BPH (> 80 gm)

Enrollment: 112 patients

Sex: Male

Ages: 45+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients suffering from LUTS secondary to infravesical obstruction from BPH with failed medical treatment
• International Prostate Symptom Score (IPSS) > 13
• a peak urinary flow rate (Qmax) < 15 ml/sec
• a prostate size ≥ 80 gm

Exclusion criteria

• presence of a urethral stricture
• neurological disorder
• bladder cancer
• prostate cancer
• previous history of bladder neck surgery or TURP

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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112 participants in 2 patient groups

holmium laser enucleation of the prostate

Active Comparator group

Description:

holmium laser enucleation of the prostate (HoLEP)

Treatment:

Procedure: holmium laser enucleation of the prostate

bipolar resection of the prostate

Active Comparator group

Description:

bipolar resection of the prostate (BPEP)

Treatment:

Procedure: Bipolar resection of the prostate