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HoLEP vs BPRP of a Large Volume BPH: a Randomised Controlled Trial

Cairo University (CU) logo

Cairo University (CU)

Status

Completed

Conditions

BPH With Urinary Obstruction
Male

Treatments

Procedure: Bipolar resection of the prostate
Procedure: holmium laser enucleation of the prostate

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

To compare bipolar resection versus holmium laser enucleation for management of large BPH.

Full description

To compare safety and efficacy of bipolar resection (BPRP) versus holmium laser enucleation (HoLEP) for management of large BPH (> 75 gm).

Enrollment

145 patients

Sex

Male

Ages

45+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients suffering from LUTS secondary to infravesical obstruction from BPH
  • failed medical treatment
  • International Prostate Symptom Score (IPSS) > 13
  • a peak urinary flow rate (Qmax) < 15 ml/sec
  • a prostate size ≥ 75 gm

Exclusion criteria

  • presence of a urethral stricture
  • neurological disorder
  • bladder cancer
  • prostate cancer
  • previous history of bladder neck surgery or TURP

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

145 participants in 2 patient groups

holmium laser enucleation of the prostate
Active Comparator group
Description:
holmium laser enucleation of the prostate (HoLEP)
Treatment:
Procedure: holmium laser enucleation of the prostate
bipolar resection of the prostate
Active Comparator group
Description:
bipolar resection of the prostate (BPEP)
Treatment:
Procedure: Bipolar resection of the prostate

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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