Home-based Exercise in COVID-19 Survivors

University of Sao Paulo

Status: Enrolling

Conditions: SARS (Severe Acute Respiratory Syndrome); SARS-CoV Infection; Covid19

Treatments: Other: Exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT04615052

4.342.082

Details and patient eligibility

About

The physical inactivity promoted by the patient's hospitalization, including those infected with the coronavirus, can lead to an important health impairment, including atrophy and loss of muscle function. Thus, a prospective study will be conducted to assess the effect of a home-based exercise training program on health outcomes and quality of life in COVID-19 survivors.

Enrollment: 50 estimated patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with COVID-19
• Positive RT-PCR test and/or serology assay to detect IgG against SARS-CoV-2 in addition to acute symptomatology compatible with the disease
• Admitted in intensive care unit

Exclusion criteria

• Cardiovascular disease
• Resting dyspnea
• Acute pulmonary embolism or pulmonary infarction
• Deep venous thromboembolism
• Uncontrolled visual or vestibular disorders
• Pregnancy
• Uncontrolled resting tachycardia
• Uncontrolled hypertension
• Uncontrolled Type II diabetes
• Acute infections
• Neurological disorders
• Patients with chronic kidney disease who are in need of hemodialysis
• Recent malignant neoplasm (<5 years)
• Autoimmune diseases
• Complex ventricular arrhythmias, atrial fibrillation or complete heart block
• Transplant patients
• Any physical disabilities that could hamper physical testing and exercise program

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups

Exercise group

Experimental group

Treatment:

Other: Exercise training

Control group

No Intervention group

Description:

The control group will receive all regular medical care and advice on healthy lifestyle including the promotion of recommended physical activity levels.