Home-based Exercise Training for COPD Patients (HOMEX-1)

University of Zurich (UZH)

Status: Completed

Conditions: Lung Diseases, Obstructive; Chronic Disease; Respiratory Disease

Treatments: Behavioral: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03461887

HOMEX-1

Details and patient eligibility

About

The aim of this study is to assess the effectiveness of a home-based exercise training program in COPD patients who have completed a pulmonary rehabilitation.

Full description

Exercise training is an important component of the management of chronic obstructive pulmonary disease (COPD) and numerous trials have shown large improvements in health-related quality of life (HRQoL) and exercise capacity in persons with COPD. However, the great majority of patients who would benefit from pulmonary rehabilitation (PR) never follow such a program. Moreover, many COPD patients are either not instructed to exercise at all or fail to adhere to exercise training at home after completing pulmonary rehabilitation.

This study evaluates an exercise training program that requires minimal equipment (i.e., only a chair and elastic bands) and can be easily implemented long-term in the patient's home-setting.

Enrollment: 123 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Signed informed consent after being informed
• Diagnosis of COPD, defined as forced expiratory volume in 1s/forced vital capacity (FEV1/FVC)<70% predicted, FEV1<80 % predicted after bronchodilation, with or without chronic symptoms (cough, sputum production) corresponding to a GOLD stage II-IV
• Completion of an inpatient or outpatient pulmonary rehabilitation not longer than 1 months ago
• Male and female patients ≥40 years of age
• Knowledge of German language to understand study material and assessments

Exclusion criteria

• Patients not able to conduct the exercise training program due to physical, cognitive or safety reasons, as judged by investigator; e.g., lower limb joint surgery within preceding 3 months, unstable cardiac disease, predominant neurological limitations.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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123 participants in 2 patient groups

Exercise intervention

Experimental group

Description:

Home-based, minimal equipment exercise training program.

Treatment:

Behavioral: Exercise

Control

No Intervention group

Description:

Usual care (study participation does not have any impact on regular treatment or treatment decisions, including participation in other exercise training programs or rehabilitation programs)