Home-based Exercise Training for COPD Patients (HOMEX-2)

University of Zurich (UZH)

Status: Completed

Conditions: Lung Diseases, Obstructive; Chronic Disease; Respiratory Disease

Treatments: Behavioral: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03654092

HOMEX-2

Details and patient eligibility

About

The aim of this study is to assess the effectiveness of a home-based exercise training program in COPD patients who did not participate in an inpatient or outpatient rehabilitation program within the last 2 years.

Full description

Exercise training is an important component of pulmonary rehabilitation (PR) the management of chronic obstructive pulmonary disease (COPD) and numerous trials have shown large improvements in health-related quality of life (HRQoL) and exercise capacity in persons with COPD. However, the great majority of patients who would benefit from PR never follow such a program. Moreover, many COPD patients are either not instructed to exercise at all or fail to adhere to exercise training at home after completing PR.

This study evaluates a newly developed exercise training program that requires minimal equipment (i.e., only a chair and elastic bands) and can be easily implemented long-term in the patient's home-setting.

Enrollment: 50 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Signed informed consent after being informed
• Diagnosis of COPD, defined as forced expiratory volume in 1s/forced vital capacity (FEV1/FVC)<70% predicted, FEV1<80 % predicted after bronchodilation, with or without chronic symptoms (cough, sputum production) corresponding to a GOLD stage II-IV
• No participation in an inpatient or outpatient pulmonary rehabilitation within the last 12 months
• Male and female patients ≥40 years of age
• Knowledge of German language to understand study material and assessments

Exclusion criteria

• Patients not able to conduct the exercise training program due to physical, cognitive or safety reasons, as judged by investigator; e.g., lower limb joint surgery within preceding 3 months, unstable cardiac disease, predominant neurological limitations.
• Planned participation in a pulmonary rehabilitation program

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Exercise intervention

Experimental group

Description:

Home-based, minimal equipment exercise training program.

Treatment:

Behavioral: Exercise

Control

No Intervention group

Description:

Usual care (study participation does not have any impact on regular treatment decisions, including participation in other exercise training programs).