Home-Based Telerehabilitation for People With Alzheimer Disease

Istanbul University - Cerrahpasa (IUC)

Status: Completed

Conditions: Alzheimer Disease

Treatments: Other: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT04606251

Kübra Nur Menengiç, IUC

Details and patient eligibility

About

The aim of this study is to investigate the effect of a physical exercise program with cognitive tasks to be applied with telerehabilitation in Alzheimer's disease, on cognitive and physical function, ability to perform daily living activities, depression and anxiety. Secondary aim is to examine the effect of the exercise application on the care burden and well-being of caregivers.

Full description

Exercise application in the study will take 6 weeks. Evaluations will be made twice, at the beginning and end of the exercise application.

Functional mobility was measured with the 5-Times Sit-and-Stand Test (5XSTS) and Timed Up and Go Test (TUG); static balance with One-Leg Stand Test; functional independence level with Functional Independence Scale (FIM); daily living activities will be evaluated with the Katz Activities of Daily Living Scale.

The general cognitive level of the cases was determined by Mini-Mental State Examination; Depressive symptoms will be measured with the Geriatric Depression Scale-Short Form, and anxiety levels will be measured with the Beck Anxiety Scale.

The care burden of caregivers will be assessed with the Zarit Care Burden Scale, and caregiver's well-being will be assessed with the Warwick-Edinburgh Mental Well-being Scale.

Primary outcome measures are Mini Mental Test, Timed Up&Go Test, and the 5-Times Sit-and-Stand Test .

Enrollment: 34 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Over 65 years old,
2. Diagnosed with Alzheimer's disease according to the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease (NINCDS-ADRDA) criteria,
3. Scoring between 0-2 points according to the Clinical Dementia Rating Scale (with mild-moderate dementia-related symptoms),
4. Have used any dementia medication such as cholinesterase inhibitors and memantine for at least the last month,
5. Mini Mental Test score between 13-24 points,
6. The caregiver living with is sufficient in the use of technology,
7. Cases who could understand the instructions given in Turkish were included in the study.

Exclusion criteria

1. Dementia with Lewy bodies, frontotemporal dementia and one of the other types of dementia,
2. Having a pulmonary, neurological, musculoskeletal or rheumatological disease that may prevent exercise,
3. Unstable medical condition (uncontrolled diabetes or hypertension, deep vein thrombosis, etc.),
4. Modified Charlson Comorbidity Index score greater than 6,
5. Receiving any rehabilitation service from an institution or person,
6. Having regular exercise habits,
7. Subjects with visual or auditory deficits or behavioral problems that would make communication difficult were not included in the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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34 participants in 2 patient groups

Arm 1: Exercise Group

Experimental group

Description:

This group will consist of the subjects taken for 6 weeks of exercise.

Treatment:

Other: Exercise

Arm 2: Control Group

No Intervention group

Description:

This group will consist of the subjects who did not receive any intervention for 6 weeks and were evaluated before and after 6 weeks.